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Vitamin c ethyl ether whitening effect

August 19, 2024
Vitamin C ethyl ether wipe face has whitening, anti-inflammatory, increase skin elasticity and other functions, contribute to skin care. 1, whitening: Vitamin C ethyl ether is a commonly used vitamin C derivative, smears on the local skin, can inhibit tyrosinase activity, reduce melanin formation, has the effect of whitening skin.
 
Vitamin C ethyl ether is a vitamin C derivative with a wide range of applications and specific synthesis methods.
In terms of use, vitamin C ethyl ether is mainly used in emulsion, skin cream, oil-in-water emulsion, whitening and freckle products and anti-aging products. It can effectively inhibit the activity of tyrosinase, thereby preventing the formation of melanin, to achieve whitening effect. Under the condition of pH 3~5, the whitening and freckle removal effect is best. In addition, vitamin C ethyl ether can also be used in cosmetics as an effective whitening ingredient to help improve skin tone and reduce skin spots ‌.
 
In terms of synthesis methods, the synthesis path of vitamin C ethyl ether mainly involves the following steps:
‌1. Condensation ‌ : Vitamin C, acetone dimethyl alcohol, DMSO and catalyst are added to the reaction tank for condensation reaction, and the reaction temperature and time are controlled. At the end of the reaction, methanol and residual acetone dimethyl alcohol were separated by neutralization and distillation.
‌2. Etheration ‌ : Sodium bicarbonate and water are added to the condensation products after distillation, and then the mixed solution obtained by pre-dissolving bromoethane in DMSO is added to the condensation products in drops for etheration reaction, and the reaction temperature and time are controlled. The reaction was followed by extraction and concentration under reduced pressure.
‌3. Hydrolysis ‌ : Concentrated hydrochloric acid, sodium bicarbonate and solvent methanol are added to the concentrated organic layer under reduced pressure for hydrolysis reaction, and the reaction temperature and time are controlled. After hydrolysis, vitamin C ethyl ether was obtained, and its purity (HPLC) could reach more than 99.5% ‌1.
In addition, vitamin C ethyl ether is widely used in daily chemical products because of its high chemical stability and hydrophilic properties. It can easily enter the dermis through the stratum corneum and be broken down by biological enzymes in the body to play the biological role of vitamin C ‌.
 
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